Wow, what a development! Through new gene editing technology named CRISPR-Cas9, researchers have developed a method to make pigs resistant to Porcine Reproductive and Respiratory Syndrome (PRRS). This is a huge game-changer!
The PRRS virus has caused major losses estimated in the hundreds of millions annually to swine operations all over the world. Losses are characterized by the millions of growing pigs either dying or requiring treatment for pneumonia, sow abortions and infertility. Universities, biological companies and research institutions have been aggressively chasing a cure or prevention program for several years to stop the PRRS virus. Unfortunately vaccination and management changes while helpful haven’t been the answer.
Now Mizzou and Genus researchers have discovered a protein, CD163 that is found on the pig’s white blood cells which releases the PRRS virus from its protective coating to infect the pig. Scientists have also discovered a method to genetically modify white blood cells so CD163 is not produced. The virus passes on through the body still locked in its protective coating. Kudos to the researchers! Gene editing is proving to be a powerful tool to improve animal health.
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